Text Box: Advances in Peripheral Nerve Regeneration and Sutureless Anastomosis in Vasculatures, Trachea, Urethra and Soft-Tissues FUTURE THERAPEUTIC MODALITIES Text Box: Groundbreaking research from Johns Hopkins and the University of Washington is leading to a paradigm shift in the surgical repair of peripheral nerves, vasculatures, tendons, trachea, intestines and urethra. Synergy between the latest advances in biomaterials, nanotechnology and neuroscience have suggested new regenerative, sutureless therapeutic modalities. Two seminal thinkers in the areas of neurologic regeneration and biomaterials respectively will present to you on the resultant possibilities, which can open up a $3 Billion/Yr market for general soft-tissue anastomosis and PNS trauma repair. This by-invitation-only complimentary evening will also feature other notable attendees from the surgical community. Please RSVP at the earliest to reserve your seat. Text Box: Highlights New nanofiber nerve guides provide regeneration rates several times better. Sutureless connectors for neurosurgery and general soft-tissue anastomoses. Fast path-to-market through 510(k). Replace autologous sural grafting even for brachial plexus trauma. Greatly reduce total surgical duration. Immense cost savings for hospitals. Text Box: Venue: DLA Piper Law Offices (Columbia Tower) 701 5th Ave # 7000 Seattle, WA 98104 Text Box: Dr. Ahmet Höke MD, PhD Director Division of Neuromuscular Diseases Department of Neurology and Neuroscience Johns Hopkins University, Baltimore, MD Text Box: Please visit us at: www.ratnerbiomedical.com Text Box: RSVP: Web: http://www.ratnerbiomedical.com/RSVP Direct: jkn@ratnerbiomedical.com or (425) 269 5812 Text Box: Panel Moderator: Dr. John Loeser MD Professor of Neurosurgery & Anesthesiology University of Washington, Seattle, WA Text Box: Date: August 28th, 2009 (Friday) Text Box: Time: 05:30 PM to 07:30 PM Text Box: Dr. Buddy Ratner PhD Director UW Engineered Biomaterials University of Washington, Seattle, WA

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